Table 2. Endocrine Disruption in Freshwater
Fish/Species Sex Land Use Location/ Study Site Caged/wild fish Vtg I T E2 GSI GD EM Possible Cause(s) Reference
Roach (Rutilus rutilus) M/F Sewage treatment plants 15 sites in England caged; 1-3 weeks +





17a-ethinylestradiol "Purdom et al., 1994"
Rainbow trout (Oncorhynchus mykiss) M Sewage treatment plants 15 sites in England and Wales caged; 3 weeks +





17a-ethinylestradiol "Sumpter and Jobling, 1995"
Rainbow trout (Oncorhynchus mykiss) M Sewage treatment plants 5 sites on River Lea in U.K. caged; 3 weeks +





17a-ethinylestradiol and alkylphenols "Harries et al., 1996"
Rainbow trout (Oncorhynchus mykiss) M Sewage treatment plants 5 sites on River Lea in U.K. caged; 3 weeks +




Estrogens and nonylphenol "Harries et al., 1997"
Rainbow trout (Oncorhynchus mykiss) M Sewage treatment plants Berlin STP 6 months +





Estrogens and nonylphenol "Hansen et al., 1998"
Roach (Rutilus rutilus) M Sewage treatment plants 8 rivers in the U.K. wild + +



Estrogens and alkylphenols "Jobling et al., 1998"
Roach (Rutilus rutilus) M Sewage treatment plants "Chelmsford STP, U.K." caged; 1 month + +




Estrogens and alkylphenols "Rodgers-Gray et al., 2000"
Rainbow trout (Oncorhynchus mykiss) M Sewage treatment plants "River Aire, U.K." caged; 3 weeks +





Alkylphenols from wool scouring plant "Sheahan et al., 2002a"
Gudgeon (Gobio gobio) M Sewage treatment plants "River Aire, U.K." wild + +




Estrogens and alkylphenols "van Aerle et al., 2001"
Rainbow trout (Oncorhynchus mykiss) M Sewage treatment plant Western Sweden caged; 2 weeks +





Estrogens and alkylphenols "Larsson et al., 1999"
Mosquitofish (Gambusia a. holbrooki) M Sewage treatment plant "Hawkesbury River, Australia " wild





Estrogens and alkylphenols "Batty and Lim, 1999"
Common carp (Cyprinus carpio) M Sewage treatment plants "St. Paul, Minnesota " wild +
NE



Estrogens "Folmar et al., 1996"
Walleye (Stizostedion vitreum) M Sewage treatment plants "St. Paul, Minnesota " wild +
+

Estrogens and alkylphenols "Folmar et al., 2001"
Walleye (Stizostedion vitreum) F Sewage treatment plants "St. Paul, Minnesota " wild +

+

Estrogens and alkylphenols "Folmar et al., 2001"
Largemouth bass (Micropterus salmoides floridanus) M Pulp and paper mill St. Johns River wild





b-Sitosterol "Sepúlveda et al., 2002"
Largemouth bass (Micropterus salmoides floridanus) F Pulp and paper mill St. Johns River wild




b-Sitosterol "Sepúlveda et al., 2002"
Whitefish (Coregonus lavaretus) M/F Pulp and paper mill "Lake Saimaa, Finland" caged; 1 month +





b-Sitosterol "Soimasuo et al., 1998"
Perch (Perca fluviatilis L.) F Pulp and paper mill "Lake Saimaa, Finland" wild





b-Sitosterol "Karels et al., 2001"
White sucker (Catostomus commersoni) M/F Pulp and paper mill "St. Maurice River, Quebec" wild




b-Sitosterol "Gagnon et al., 1994"
White sucker (Catostomus commersoni) M/F Pulp and paper mill "Lake Superior, Canada" wild



b-Sitosterol "McMaster et al., 1991"
Mosquitofish (Gambusia holbrooki) F Pulp and paper mill "St. John's River, Florida" wild





b-Sitosterol "Bortone and Cody, 1999"
Mosquitofish (Gambusia holbrooki) F Pulp and paper mill "Perdido Bay, Florida" wild





b-Sitosterol "Cody and Bortone, 1997"
Mosquitofish (Gambusia holbrooki) F Pulp and paper mill "Fenholloway River, Florida" wild





b-Sitosterol "Jenkins et al., 2001"
Channel catfish (Ictalurus punctatus) F Sugar beet processing plant "Red River, North Dakota" wild





b-Sitosterol "Hegrenes, 1999"
Largemouth bass (Micropterus salmoides) M/F "Power plant, chemical manufacture" "Escambia/Blackwater River, Florida" wild +




Contaminants "Orlando et al., 1999"
Common carp (Cyprinus carpio) M General survey Various locations in U.S. wild +/NE
–/NE

–/NE
Contaminants "Goodbred et al., 1997"
Common carp (Cyprinus carpio) F General survey Various locations in U.S. wild


–/NE


Contaminants "Goodbred et al., 1997"
Fathead minnow (Pimphales promelas) M/F General survey Mississippi River wild NE





None "Parks et al., 1997"

"M/F, male and female fish collected in study and effects same in both sexes; NE, no effect; Vtg, vitellogenin; I, intersex condition; T, testosterone; E2, 17b-estradiol; "
"GSI, gonadosomatic index; GD, gonadal development; EM effect on external male/female morphology"